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Cheminformatics approach to identify andrographolide derivatives as dual inhibitors of methyltransferases (nsp14 and nsp16) of SARS-CoV-2

Abstract The Covid-19 pandemic outbreak has accelerated tremendous efforts to discover a therapeutic strategy that targets severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to control viral infection. Various viral proteins have been identified as potential drug targets, however, to date,...

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Bibliografiske detaljer
Principais autores: Jobin Thomas, Anupam Ghosh, Shivendu Ranjan, Jitendra Satija
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2024-04-01
Serier:Scientific Reports
Fag:
Online adgang:https://doi.org/10.1038/s41598-024-58532-7
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