Noncoding variation near UBE2E2 orchestrates cardiometabolic pathophenotypes through polygenic effectors

Mechanisms underpinning signals from genome-wide association studies remain poorly understood, particularly for noncoding variation and for complex diseases such as type 2 diabetes mellitus (T2D) where pathogenic mechanisms in multiple different tissues may be disease driving. One approach is to stu...

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Detalhes bibliográficos

Principais autores:	Yang Zhang, Natalie L. David, Tristan Pesaresi, Rosemary E. Andrews, G.V. Naveen Kumar, Hongyin Chen, Wanning Qiao, Jinzhao Yang, Kareena Patel, Tania Amorim, Ankit X. Sharma, Silvia Liu, Matthew L. Steinhauser
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical investigation 2025-01-01
coleção:	JCI Insight
Assuntos:	Endocrinology Genetics
Acesso em linha:	https://doi.org/10.1172/jci.insight.184140
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