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Heparan Sulfate Proteoglycans and Viral Attachment: True Receptors or Adaptation Bias?

Heparan sulfate proteoglycans (HSPG) are composed of unbranched, negatively charged heparan sulfate (HS) polysaccharides attached to a variety of cell surface or extracellular matrix proteins. Widely expressed, they mediate many biological activities, including angiogenesis, blood coagulation, devel...

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Principais autores: Valeria Cagno, Eirini D. Tseligka, Samuel T. Jones, Caroline Tapparel
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2019-07-01
Serier:Viruses
Fag:
viral attachment receptor
heparan sulfate proteoglycans
HSPG
syndecans
glypicans
viral adaptation
intra-host adaptation
tropism
broad-spectrum antivirals
viral binding
Online adgang:https://www.mdpi.com/1999-4915/11/7/596
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