Machine learning based intratumor heterogeneity related signature for prognosis and drug sensitivity in breast cancer

Abstract Intratumor heterogeneity (ITH) is involved in tumor evolution and drug resistance. Drug sensitivity shows discrepancy in different breast cancer (BRCA) patients due to ITH. The genes mediating ITH in BRCA and their role in predicting prognosis and drug sensitivity is not yet elucidated. An...

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Principais autores:	Hongcai Chen, Minna Chen, Cui Yang, Tingting Tang, Wende Wang, Wenwu Xue
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2025-03-01
Serija:	Scientific Reports
Teme:	Intratumor heterogeneity Breast cancer Biomarker Immunotherapy Bioinformatics
Online dostop:	https://doi.org/10.1038/s41598-025-92695-1
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