Machine learning based intratumor heterogeneity related signature for prognosis and drug sensitivity in breast cancer

Abstract Intratumor heterogeneity (ITH) is involved in tumor evolution and drug resistance. Drug sensitivity shows discrepancy in different breast cancer (BRCA) patients due to ITH. The genes mediating ITH in BRCA and their role in predicting prognosis and drug sensitivity is not yet elucidated. An...

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主要な著者:	Hongcai Chen, Minna Chen, Cui Yang, Tingting Tang, Wende Wang, Wenwu Xue
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Portfolio 2025-03-01
シリーズ:	Scientific Reports
主題:	Intratumor heterogeneity Breast cancer Biomarker Immunotherapy Bioinformatics
オンライン･アクセス:	https://doi.org/10.1038/s41598-025-92695-1
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