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IL-33-mediated mast cell and eosinophil function requires isoprenylation

IntroductionAllergic disease is a common and symptomatically heterogeneous group of inflammatory disorders marked by overactive Th2 and mast cell (MC) responses along with eosinophil infiltration. Treatment options require continual assessment due to breakthrough symptoms on standard regimens. One a...

Deskribapen osoa

Gorde:
Egile Nagusiak: Jason R. Burchett, Aditya Kotha, Destiny T. Davis, Kaitlyn G. Jackson, Jordan M. Dailey, Tania D. Maldonado, Tamara T. Haque, Zakaria Y. Hussain, John M. Ching, Pamela Frischmeyer-Guerrerio, Said M. Sebti, John J. Ryan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2025-12-01
Saila:Frontiers in Immunology
Gaiak:
IL-33
inflammation
simvastatin
mast cells
eosinophils
isoprenylation
Sarrera elektronikoa:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1662170/full
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