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IL-33-mediated mast cell and eosinophil function requires isoprenylation

IntroductionAllergic disease is a common and symptomatically heterogeneous group of inflammatory disorders marked by overactive Th2 and mast cell (MC) responses along with eosinophil infiltration. Treatment options require continual assessment due to breakthrough symptoms on standard regimens. One a...

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Uloženo v:
Hlavní autoři: Jason R. Burchett, Aditya Kotha, Destiny T. Davis, Kaitlyn G. Jackson, Jordan M. Dailey, Tania D. Maldonado, Tamara T. Haque, Zakaria Y. Hussain, John M. Ching, Pamela Frischmeyer-Guerrerio, Said M. Sebti, John J. Ryan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2025-12-01
Edice:Frontiers in Immunology
Témata:
IL-33
inflammation
simvastatin
mast cells
eosinophils
isoprenylation
On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1662170/full
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