क्यूआर कोड

Biological properties of α-actinin-2 and its role and mechanisms in disease development

α-Actinin-2 (encoded by the ACTN2 gene) is a critical cytoskeletal protein predominantly expressed in skeletal and cardiac muscle, where it anchors actin filaments to the sarcomeric Z-disk. While its structural role is well-established, emerging evidence increasingly implicates ACTN2 dysfunction in...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Juan Meng, Shu-qiong Xu, Qi Deng, Ling-ling Jiang, Dan-Ping Huang, Qing-song Wang, Yong-Kang Wu
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2026-04-01
श्रृंखला:Frontiers in Physiology
विषय:
ACTN2
biomarker
cardiomyopathy
sarcomere
therapeutic target
α-actinin-2
ऑनलाइन पहुंच:https://www.frontiersin.org/articles/10.3389/fphys.2026.1794324/full
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