Adenosine deaminase acting on RNA-1 (ADAR1) inhibits HIV-1 replication in human alveolar macrophages.

While exploring the effects of aerosol IFN-γ treatment in HIV-1/tuberculosis co-infected patients, we observed A to G mutations in HIV-1 envelope sequences derived from bronchoalveolar lavage (BAL) of aerosol IFN-γ-treated patients and induction of adenosine deaminase acting on RNA 1 (ADAR1) in the...

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Autors principals:	Michael D Weiden, Satomi Hoshino, David N Levy, Yonghua Li, Rajnish Kumar, Sean A Burke, Rodney Dawson, Catarina E Hioe, William Borkowsky, William N Rom, Yoshihiko Hoshino
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2014-01-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC4182706?pdf=render
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