Fluxomics reveals cellular and molecular basis of increased renal ammoniagenesis
Abstract The kidney plays a critical role in excreting ammonia during metabolic acidosis and liver failure. The mechanisms behind this process have been poorly explored. The present study combines results of in vivo experiments of increased total ammoniagenesis with systems biology modeling, in whic...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Portfolio
2022-12-01
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| Col·lecció: | npj Systems Biology and Applications |
| Accés en línia: | https://doi.org/10.1038/s41540-022-00257-2 |
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