The novel GSDMD inhibitor GI‐Y2 exerts antipyroptotic effects to reduce atherosclerosis

Abstract Introduction Gasdermin D (GSDMD) and the pyroptosis it mediates are importantly involved in cardiovascular diseases (CVDs). Identifying and developing new inhibitors of GSDMD could be a promising strategy for treating pyroptosis‐mediated diseases, such as atherosclerosis. Objectives We aime...

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Detalhes bibliográficos

Principais autores:	Xiaoxi Fan, Zhenfeng Cheng, Ruiyin Shao, Keke Ye, Xudong Chen, Xueli Cai, Shanshan Dai, Zhixuan Tang, Si Shi, Wenyuan Zheng, Weijian Huang, Jibo Han, Bozhi Ye
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-03-01
coleção:	Clinical and Translational Medicine
Assuntos:	atherosclerosis gasdermin D macrophage pyroptosis
Acesso em linha:	https://doi.org/10.1002/ctm2.70263
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