Angiotensin-(1–7) suppresses airway inflammation and airway remodeling via inhibiting ATG5 in allergic asthma

Abstract Background Angiotensin (Ang)-(1–7) can reduce airway inflammation and airway remodeling in allergic asthma. Autophagy-related 5 (ATG5) has attracted wide attentions in asthma. However, the effects of Ang-(1–7) on ATG5-mediated autophagy in allergic asthma are unclear. Methods In this study,...

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Detalles Bibliográficos

Principais autores:	Jianfeng Xu, Zhenyu Yu, Xueping Liu
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2023-11-01
Series:	BMC Pulmonary Medicine
Assuntos:	Transforming growth factor (TGF)-β1 Type 2 helper T cell (Th2) cytokines Autophagy related (ATG)-5 ATG5 knockout (ATG5−/−) mice
Acceso en liña:	https://doi.org/10.1186/s12890-023-02719-7
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