Structure/Function Studies on the Activation Motif of Two Non-Mammalian Mrap1 Orthologs, and Observations on the Phylogeny of Mrap1, Including a Novel Characterization of an Mrap1 from the Chondrostean Fish, <i>Polyodon spathula</i>
In derived bony vertebrates, activation of the melanocortin-2 receptor (Mc2r) by its ACTH ligand requires chaperoning by the Mc2r accessory protein (Mrap1). The N-terminal domain of the non-mammalian tetrapod MRAP1 from chicken (c; <i>Gallus gallus</i>) has the putative activation motif, W<sup>18</s...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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MDPI AG
2022-11-01
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| Saila: | Biomolecules |
| Gaiak: | |
| Sarrera elektronikoa: | https://www.mdpi.com/2218-273X/12/11/1681 |
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