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Structure/Function Studies on the Activation Motif of Two Non-Mammalian Mrap1 Orthologs, and Observations on the Phylogeny of Mrap1, Including a Novel Characterization of an Mrap1 from the Chondrostean Fish, <i>Polyodon spathula</i>

In derived bony vertebrates, activation of the melanocortin-2 receptor (Mc2r) by its ACTH ligand requires chaperoning by the Mc2r accessory protein (Mrap1). The N-terminal domain of the non-mammalian tetrapod MRAP1 from chicken (c; <i>Gallus gallus</i>) has the putative activation motif, W<sup>18</s...

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Ngā kaituhi matua: Robert M. Dores, Greer McKinley, Audrey Meyers, Morgan Martin, Ciaran A. Shaughnessy
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2022-11-01
Rangatū:Biomolecules
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Urunga tuihono:https://www.mdpi.com/2218-273X/12/11/1681
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