Genome-wide profiling of salivary promoter-region DNA methylation in periodontitis: the Tromsø Study

Abstract Background Methylation of DNA is an epigenetic reversible process that regulates gene expression. Aberrant promoter methylation is associated with chronic inflammation; however, the genome-wide DNA promoter methylation signature in periodontitis remains unexplored. Methods The present study...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Natalia Petrenya, Birgitta Jönsson, Elin Hadler-Olsen, Lena Larsson, Arnar Flatberg, Vidar Beisvåg, Gro Eirin Holde, Svetlana N. Zykova, Farah Asa’ad
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2026-02-01
Schriftenreihe:	BMC Medical Genomics
Schlagworte:	DNA methylation Periodontitis Epigenomics Enrichment analysis Network visualization Illumina methylation BeadChip technology
Online-Zugang:	https://doi.org/10.1186/s12920-026-02319-4
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