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Genome-wide profiling of salivary promoter-region DNA methylation in periodontitis: the Tromsø Study

Abstract Background Methylation of DNA is an epigenetic reversible process that regulates gene expression. Aberrant promoter methylation is associated with chronic inflammation; however, the genome-wide DNA promoter methylation signature in periodontitis remains unexplored. Methods The present study...

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Principais autores: Natalia Petrenya, Birgitta Jönsson, Elin Hadler-Olsen, Lena Larsson, Arnar Flatberg, Vidar Beisvåg, Gro Eirin Holde, Svetlana N. Zykova, Farah Asa’ad
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-02-01
Serier:BMC Medical Genomics
Fag:
DNA methylation
Periodontitis
Epigenomics
Enrichment analysis
Network visualization
Illumina methylation BeadChip technology
Online adgang:https://doi.org/10.1186/s12920-026-02319-4
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