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Mechanism of inducible nitric oxide synthase exclusion from mycobacterial phagosomes.

Mycobacterium tuberculosis is sensitive to nitric oxide generated by inducible nitric oxide synthase (iNOS). Consequently, to ensure its survival in macrophages, M. tuberculosis inhibits iNOS recruitment to its phagosome by an unknown mechanism. Here we report the mechanism underlying this process,...

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書誌詳細
主要な著者: Alexander S Davis, Isabelle Vergne, Sharon S Master, George B Kyei, Jennifer Chua, Vojo Deretic
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2007-12-01
シリーズ:PLoS Pathogens
オンライン・アクセス:https://doi.org/10.1371/journal.ppat.0030186
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