Transcriptional activation of REST by Sp1 in Huntington's disease models.
In Huntington's disease (HD), mutant huntingtin (mHtt) disrupts the normal transcriptional program of disease neurons by altering the function of several gene expression regulators such as Sp1. REST (Repressor Element-1 Silencing Transcription Factor), a key regulator of neuronal differentiation, is...
保存先:
| 主要な著者: | , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science (PLoS)
2010-12-01
|
| シリーズ: | PLoS ONE |
| オンライン･アクセス: | https://doi.org/10.1371/journal.pone.0014311 |
| タグ: |
タグなし, このレコードへの初めてのタグを付けませんか!
|