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Tissue signatures influence the activation of intrahepatic CD8+ T cells against malaria sporozoites

Plasmodium sporozoites and liver stages express antigens that are targeted to the MHC-Class I antigen-processing pathway. After the introduction of Plasmodium sporozoites by Anopheles mosquitoes, bone marrow-derived dendritic cells in skin-draining lymph nodes are the first cells to cross-present pa...

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Bibliografiske detaljer
Principais autores: Alexandre eMorrot, Mauricio Martins eRodrigues
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014-08-01
Serier:Frontiers in Microbiology
Fag:
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00440/full
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