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Plasmodium sporozoites induce regulatory macrophages.

Professional antigen-presenting cells (APCs), like macrophages (Mϕs) and dendritic cells (DCs), are central players in the induction of natural and vaccine-induced immunity to malaria, yet very little is known about the interaction of SPZ with human APCs. Intradermal delivery of whole-sporozoite vac...

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Principais autores: Béatrice M F Winkel, Leonard R Pelgrom, Roos van Schuijlenburg, Els Baalbergen, Munisha S Ganesh, Heleen Gerritsma, Clarize M de Korne, Nikolas Duszenko, Marijke C C Langenberg, Séverine C Chevalley-Maurel, Hermelijn H Smits, Esther C de Jong, Bart Everts, Blandine Franke-Fayard, Meta Roestenberg
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2020-09-01
coleção:PLoS Pathogens
Acesso em linha:https://doi.org/10.1371/journal.ppat.1008799
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