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Reduced virulence in tigecycline-resistant Klebsiella pneumoniae caused by overexpression of ompR and down-regulation of ompK35

Abstract Background The development of tigecycline resistance in hypervirulent Klebsiella pneumoniae strains has resulted in decreased virulence that is associated with reduced production of capsular polysaccharides (CPS). In this study, we investigated the mechanisms that link tigecycline susceptib...

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Detalhes bibliográficos
Principais autores: Suyeon Park, Hyunkeun Kim, Kwan Soo Ko
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-03-01
coleção:Journal of Biomedical Science
Assuntos:
Acesso em linha:https://doi.org/10.1186/s12929-023-00910-w
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