Scarless excision of an insertion sequence in the OmpK36 promoter restores meropenem susceptibility in a non-carbapenemase-producing Klebsiella pneumoniae

Carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a significant global health challenge due to its limited treatment options and high mortality rates. Meanwhile, the prevalence of non-carbapenemase-producing CRKP (NC-CRKP) strains is increasing, but their resistance mechanisms remain less unde...

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Autors principals:	Yingying Du, Tong Liu, Yuanzhi Gong, Yinghua Yuan, Yunlou Zhu, Min Hao, Yuhao Liu, Sheng Wang
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis Group 2025-12-01
Col·lecció:	Emerging Microbes and Infections
Matèries:	Non-carbapenemase-producing Klebsiella pneumoniae meropenem resistance OmpK36 deficiency promoter insertion sequence
Accés en línia:	https://www.tandfonline.com/doi/10.1080/22221751.2025.2503922
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