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Functional interaction between S100A1 and MDM2 may modulate p53 signaling in normal and malignant endometrial cells

Abstract Background S100A1 expression is deregulated in a variety of human malignancies, but its role in normal and malignant endometrial cells is unclear. Methods We used endometrial carcinoma (Em Ca) cell lines to evaluate the physical and functional interaction of S100A1 with p53 and its negative...

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Principais autores: Mayu Nakagawa, Shyoma Higuchi, Miki Hashimura, Yasuko Oguri, Toshihide Matsumoto, Ako Yokoi, Yu Ishibashi, Takashi Ito, Makoto Saegusa
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2022-02-01
Series:BMC Cancer
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Acceso en liña:https://doi.org/10.1186/s12885-022-09249-1
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