PTEN overexpression and nuclear β-catenin stabilization promote morular differentiation through induction of epithelial–mesenchymal transition and cancer stem cell-like properties in endometrial carcinoma

Abstract Background Although a lack of functional PTEN contributes to tumorigenesis in a wide spectrum of human malignancies, little is known about the functional role of its overexpression in the tumors. The current study focused on PTEN overexpression in endometrial carcinoma (Em Ca). Methods The...

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מידע ביבליוגרפי

Principais autores:	Ako Yokoi, Marina Minami, Miki Hashimura, Yasuko Oguri, Toshihide Matsumoto, Yoshinori Hasegawa, Mayu Nakagawa, Yu Ishibashi, Takashi Ito, Kensuke Ohhigata, Youhei Harada, Naomi Fukagawa, Makoto Saegusa
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2022-11-01
סדרה:	Cell Communication and Signaling
נושאים:	PTEN β-catenin EBP50 Cancer stem cell Endometrial carcinoma Morule
גישה מקוונת:	https://doi.org/10.1186/s12964-022-00999-w
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!