Mutagenicity and antimutagenicity of (−)-hinokinin a trypanosomicidal compound measured by <it>Salmonella</it> microsome and comet assays

<p>Abstract</p> <p>Background</p> <p>The dibenzylbutyrolactone lignan (−)-hinokinin (HK) was derived by partial synthesis from (−)-cubebin, isolated from the dry seeds of the pepper, <it>Piper cubeba</it>. Considering the good trypanosomicidal activity of HK and recalling that natural products are p...

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Detalhes bibliográficos

Principais autores:	Resende Flávia Aparecida, Barbosa Lilian Cristina, Tavares Denise Crispim, de Camargo Mariana Santoro, de Souza Rezende Karen Cristina, e Silva Márcio Luis de Andrade, Varanda Eliana Aparecida
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2012-10-01
coleção:	BMC Complementary and Alternative Medicine
Assuntos:	Hinokinin Ames test Comet assay Mutagenicity Antimutagenicity
Acesso em linha:	http://www.biomedcentral.com/1472-6882/12/203
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