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Mutagenicity and antimutagenicity of (−)-hinokinin a trypanosomicidal compound measured by <it>Salmonella</it> microsome and comet assays

<p>Abstract</p> <p>Background</p> <p>The dibenzylbutyrolactone lignan (−)-hinokinin (HK) was derived by partial synthesis from (−)-cubebin, isolated from the dry seeds of the pepper, <it>Piper cubeba</it>. Considering the good trypanosomicidal activity of HK and recalling that natural products are p...

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Hlavní autoři: Resende Flávia Aparecida, Barbosa Lilian Cristina, Tavares Denise Crispim, de Camargo Mariana Santoro, de Souza Rezende Karen Cristina, e Silva Márcio Luis de Andrade, Varanda Eliana Aparecida
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2012-10-01
Edice:BMC Complementary and Alternative Medicine
Témata:
Hinokinin
Ames test
Comet assay
Mutagenicity
Antimutagenicity
On-line přístup:http://www.biomedcentral.com/1472-6882/12/203
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