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T cells with increased responsiveness cause obesity in mice without diet intervention

Summary: Obesity is a complex multicausal disease that can cause morbidity and mortality, and there is need for improved knowledge on the underlying mechanisms. Using a mouse model of increased T cell responsiveness, we show that development of obesity can be driven by immune cells. This was confirm...

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Autores principales: Ida Gregersen, Xiang Y. Kong, Sander Kooijman, Håvard Foyn, Helene Grannes, Maria B. Olsen, Anna M. Lone, Kuan Yang, Ana Quiles-Jiménez, Marianne Tran, Jonas Øgaard, Filip M. Segers, Azita Rashidi, Ellen Lund Sagen, Knut H. Lauritzen, Amanda C.M. Pronk, Jan Freark de Boer, Kirsten B. Holven, Espen Melum, Pål Aukrust, Kjetil Taskén, Sverre Holm, Patrick C.N. Rensen, Tuva B. Dahl, Bente Halvorsen
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2024-04-01
Colección:iScience
Materias:
Immunology
Nutrition
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2589004224006928
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