Recombinant BCG vaccine expressing multistage antigens of Mycobacterium tuberculosis provides long-term immunity against tuberculosis in BALB/c mice

Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) persistently kills nearly 1.5 million lives per year in the world, whereas the only licensed TB vaccine BCG exhibits unsatisfactory efficacy in adults. Taking BCG as a vehicle to express Mtb antigens is a promising way to enhance its effic...

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Bibliografische Detailangaben

Hauptverfasser:	Danang Fang, Ruihuan Wang, Xueting Fan, Machao Li, Chenyu Qian, Bin Cao, Jinjie Yu, Haican Liu, Yongliang Lou, Kanglin Wan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis Group 2024-12-01
Schriftenreihe:	Human Vaccines & Immunotherapeutics
Schlagworte:	Tuberculosis Mycobacterium tuberculosis recombinant BCG vaccine multicomponent fusion antigen cytokine
Online-Zugang:	https://www.tandfonline.com/doi/10.1080/21645515.2023.2299607
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