Dynamics and necessity of SIRT1 for maternal–zygotic transition

Abstract Dynamic changes in maternal‒zygotic transition (MZT) require complex regulation of zygote formation, maternal transcript decay, embryonic genome activation (EGA), and cell cycle progression. Although these changes are well described, some key regulatory factors are still elusive. Sirtuin-1...

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Autores principales:	Jan Nevoral, David Drutovic, Michaela Vaskovicova, Michal Benc, Frantisek Liska, Iveta Valentova, Sara Stachovicova, Jan Kubovciak, Jirina Havrankova, Miki Shavit, Ladan Monsef, Maria Iniesta-Cuerda, Tereza Zalmanova, Petr Hosek, Frantisek Strejcek, Milena Kralickova, Jaroslav Petr
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2024-09-01
Colección:	Scientific Reports
Materias:	Oocyte, zygote Embryo Embryonic genome activation Epigenetics Histone deacetylase
Acceso en línea:	https://doi.org/10.1038/s41598-024-72595-6
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