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Dynamics and necessity of SIRT1 for maternal–zygotic transition

Abstract Dynamic changes in maternal‒zygotic transition (MZT) require complex regulation of zygote formation, maternal transcript decay, embryonic genome activation (EGA), and cell cycle progression. Although these changes are well described, some key regulatory factors are still elusive. Sirtuin-1...

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Furkejuvvon:
Váldodahkkit: Jan Nevoral, David Drutovic, Michaela Vaskovicova, Michal Benc, Frantisek Liska, Iveta Valentova, Sara Stachovicova, Jan Kubovciak, Jirina Havrankova, Miki Shavit, Ladan Monsef, Maria Iniesta-Cuerda, Tereza Zalmanova, Petr Hosek, Frantisek Strejcek, Milena Kralickova, Jaroslav Petr
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Nature Portfolio 2024-09-01
Ráidu:Scientific Reports
Fáttát:
Oocyte, zygote
Embryo
Embryonic genome activation
Epigenetics
Histone deacetylase
Liŋkkat:https://doi.org/10.1038/s41598-024-72595-6
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