An in-frame deletion mutation in MLH1 drives Lynch syndrome-associated colorectal cancer
Abstract Lynch syndrome (LS) is the most common inherited disorder predisposing individuals to colorectal cancer (CRC). It results from germline defects in DNA mismatch repair (MMR) genes, which are critical for maintaining genomic integrity. Here, we demonstrate that the expression of the MMR genes...
Tallennettuna:
| Päätekijät: | , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BMC
2025-07-01
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| Sarja: | BMC Cancer |
| Aiheet: | |
| Linkit: | https://doi.org/10.1186/s12885-025-14554-6 |
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