Huntingtin-mediated axonal transport requires arginine methylation by PRMT6

Summary: The huntingtin (HTT) protein transports various organelles, including vesicles containing neurotrophic factors, from embryonic development throughout life. To better understand how HTT mediates axonal transport and why this function is disrupted in Huntington’s disease (HD), we study vesicl...

Descripció completa

Dades bibliogràfiques

Autors principals:	Alice Migazzi, Chiara Scaramuzzino, Eric N. Anderson, Debasmita Tripathy, Ivó H. Hernández, Rogan A. Grant, Michela Roccuzzo, Laura Tosatto, Amandine Virlogeux, Chiara Zuccato, Andrea Caricasole, Tamara Ratovitski, Christopher A. Ross, Udai B. Pandey, José J. Lucas, Frédéric Saudou, Maria Pennuto, Manuela Basso
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2021-04-01
Col·lecció:	Cell Reports
Matèries:	huntingtin Huntington’s disease axonal transport arginine methylation PRMT6 protein post-translational modification
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2211124721002941
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!