Detection of IDH mutation in glioma by desorption electrospray ionization (DESI) tandem mass spectrometry

Abstract Desorption electrospray ionization (DESI) tandem mass spectrometry (MS) is used to assess mutation status of isocitrate dehydrogenase (IDH) in human gliomas. Due to the diffuse nature of gliomas, total gross resection is not normally achieved during surgery, leading to tumor recurrence. The...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Mahdiyeh Shahi, Steven Pringle, Michael Morris, Diogo Moniz Garcia, Alfredo Quiñones-Hinojosa, R. Graham Cooks
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Portfolio 2024-11-01
Sarja:	Scientific Reports
Aiheet:	Multiple reaction monitoring (MRM) 2-hydroxyglutarate Oncometabolite Molecular diagnostics Brain cancer Ambient ionization
Linkit:	https://doi.org/10.1038/s41598-024-77044-y
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