A proof-of-concept study towards physiologically based kinetic (PBK) modeling in agricultural operator risk assessment

Abstract Plant protection products (PPP) contain active substance(s) and co-formulants. As complex mixtures, PPPs are susceptible to toxicokinetic or toxicodynamic interactions, enhancing toxicity. Considering these interactions is crucial to avoid underestimating risk. In vitro testing identifies t...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Yemurai Musengi, Vikas Kumar, Deepika Deepika, Alfonsina Paola D’Ambrosio Melendrez, Philip Marx-Stoelting, Denise Bloch
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Springer Nature 2026-03-01
Цуврал:	Discover Toxicology
Нөхцлүүд:	Plant protection product risk assessment Kinetic interactions CYP enzymes Fraction unbound In vitro-in vivo extrapolation (IVIVE) Physiologically based kinetic (PBK)
Онлайн хандалт:	https://doi.org/10.1007/s44339-026-00052-2
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!