Progranulin and GPNMB: interactions in endo-lysosome function and inflammation in neurodegenerative disease
Abstract Background Alterations in progranulin (PGRN) expression are associated with multiple neurodegenerative diseases (NDs), including frontotemporal dementia (FTD), Alzheimer’s disease (AD), Parkinson’s disease (PD), and lysosomal storage disorders (LSDs). Recently, the loss of PGRN was shown to...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2023-11-01
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| coleção: | Journal of Neuroinflammation |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s12974-023-02965-w |
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