Colchicine prevents oxidative stress-induced endothelial cell senescence via blocking NF-κB and MAPKs: implications in vascular diseases

Abstract Background Smoking, alcohol abuse, and hypertension are – among others, potential risk factors for cardiovascular diseases. These risk factors generate oxidative stress and cause oxidative stress-induced DNA damage, resulting in cellular senescence and senescence-associated secretory phenot...

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Главные авторы:	Huakang Zhou, Dilaware Khan, Sajid Muhammad Hussain, Norbert Gerdes, Carsten Hagenbeck, Majeed Rana, Jan Frederick Cornelius, Sajjad Muhammad
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2023-11-01
Серии:	Journal of Inflammation
Предметы:	Oxidative stress Endothelial cells Cellular senescence Inflammation Colchicine NFκ-B
Online-ссылка:	https://doi.org/10.1186/s12950-023-00366-7
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