Colchicine prevents oxidative stress-induced endothelial cell senescence via blocking NF-κB and MAPKs: implications in vascular diseases

Abstract Background Smoking, alcohol abuse, and hypertension are – among others, potential risk factors for cardiovascular diseases. These risk factors generate oxidative stress and cause oxidative stress-induced DNA damage, resulting in cellular senescence and senescence-associated secretory phenot...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Huakang Zhou, Dilaware Khan, Sajid Muhammad Hussain, Norbert Gerdes, Carsten Hagenbeck, Majeed Rana, Jan Frederick Cornelius, Sajjad Muhammad
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2023-11-01
Schriftenreihe:	Journal of Inflammation
Schlagworte:	Oxidative stress Endothelial cells Cellular senescence Inflammation Colchicine NFκ-B
Online-Zugang:	https://doi.org/10.1186/s12950-023-00366-7
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!