Deciphering the role of protein kinase A in the control of FoxP3 expression in regulatory T cells in health and autoimmunity

Abstract The molecular mechanisms that govern differential T cell development from CD4+CD25-conventional T (Tconv) into CD4+CD25+ forkhead-box-P3+ (FoxP3+) inducible regulatory T (iTreg) cells remain unclear. Herein, we investigated the relative contribution of protein kinase A (PKA) in this process...

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Detalhes bibliográficos

Principais autores:	Maria Teresa Lepore, Sara Bruzzaniti, Claudia La Rocca, Clorinda Fusco, Fortunata Carbone, Maria Mottola, Bruno Zuccarelli, Roberta Lanzillo, Vincenzo Brescia Morra, Giorgia Teresa Maniscalco, Salvatore De Simone, Claudio Procaccini, Antonio Porcellini, Veronica De Rosa, Mario Galgani, Silvana Cassano, Giuseppe Matarese
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-07-01
coleção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-024-68098-z
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