Identification of secretory protein related biomarkers for primary biliary cholangitis based on machine learning and experimental validation

Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease that causes bile duct damage, liver fibrosis, and cirrhosis, significantly affecting patients’ lives and healthcare costs. Early diagnosis is critical but is hindered by the limited sensitivity of existing biomarkers, particular...

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Bibliografiske detaljer

Principais autores:	Xu Zihao, Cai Yue, Liu Yifan, Xu Jun, Guo Sheng, Zhou Lihan, Ji Yang, Zhan Lei, Cheng Liangbin
Format:	Artigo
Sprog:	Inglês
Udgivet:	De Gruyter 2025-12-01
Serier:	Open Life Sciences
Fag:	biomarkers bioinformatics machine learning secretory proteins primary biliary cholangitis
Online adgang:	https://doi.org/10.1515/biol-2025-1192
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