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The role of mitochondria-related key genes in primary biliary cholangitis was analyzed based on transcriptome sequencing data

IntroductionMitochondrial dysfunction is implicated in the pathogenesis of primary biliary cholangitis (PBC), but the roles of mitochondria-related genes (MRGs) remain unclear. We aimed to identify key MRGs associated with PBC and validate their expression at transcriptional and protein levels.Metho...

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Principais autores: Yanping Tao, Lei Zhong, Qihua Shen, Xiaofan Zhang, Xuyun Xu, Runlin Feng
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2025-10-01
סדרה:Frontiers in Immunology
נושאים:
primary biliary cholangitis
SHANK2
TGM2
mitochondria
bioinformatics
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1644682/full
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