Portrayed the development of activated T cell to exhausted T cell based on the ratio of CD28 to CTLA4
Abstract T cell exhaustion, to some extent, limits the clearance of viruses and tumor cells and accounts for the poor effectiveness of immune therapy. The generally accepted classification of exhausted T cells assigns them as progenitor and terminal statuses. However, the outcome of immune therapy b...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer
2026-01-01
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| Serie: | Cancer Immunology, Immunotherapy |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1007/s00262-025-04297-5 |
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