Oceanapiside, a Marine Natural Product, Targets the Sphingolipid Pathway of Fluconazole-Resistant <i>Candida glabrata</i>

Oceanapiside (OPS), a marine natural product with a novel bifunctional sphingolipid structure, is fungicidal against fluconazole-resistant <i>Candida glabrata</i> at 10 μg/mL (15.4 μM). The fungicidal effect was observed at 3 to 4 h after exposure to cells. Cytological and morphological studies reve...

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Principais autores:	Doralyn S. Dalisay, Evan W. Rogers, Tadeusz F. Molinski
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-02-01
coleção:	Marine Drugs
Assuntos:	antifungal Porifera azole long-chain base sphingolipid
Acesso em linha:	https://www.mdpi.com/1660-3397/19/3/126
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