Targeting iRhom2/ADAM17 attenuates COVID-19-induced cytokine release from cultured lung epithelial cells

The COVID-19 pandemic, caused by SARS-CoV-2, continues to pose a significant global health challenge, with acute respiratory distress syndrome (ARDS) being a major cause of mortality. Excessive cytokine release (cytokine storm) has been causally related to COVID-19-associated ARDS. While TNF-α inhib...

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Detalhes bibliográficos

Principais autores:	Vitoria Mattos Pereira, Amit Thakar, Sreejayan Nair
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-09-01
Colecção:	Biochemistry and Biophysics Reports
Assuntos:	ADAM17 Cytokines Inflammation Lung SARS-COV-2 TNF-α
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405580824001754
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