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Neuronal activity triggers secretory autophagy to mediate the extracellular release of SNCA/α-synuclein

Autophagy has two distinct pathways, degradation and secretion. Autophagic degradation plays a pivotal role in cellular homeostasis by the formation of a double-membrane autophagosome in concert with numerous ATG (autophagy-related) proteins. However, the mechanism that mediates autophagic secretion...

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Hlavní autoři: Yoshitsugu Nakamura, Shigeki Arawaka
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis Group 2024-12-01
Edice:Autophagy Reports
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On-line přístup:https://www.tandfonline.com/doi/10.1080/27694127.2024.2410683
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