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Temporal and spatial staging of lung alveolar regeneration is determined by the grainyhead transcription factor Tfcp2l1

Summary: Alveolar epithelial type 2 (AT2) cells harbor the facultative progenitor capacity in the lung alveolus to drive regeneration after lung injury. Using single-cell transcriptomics, software-guided segmentation of tissue damage, and in vivo mouse lineage tracing, we identified the grainyhead t...

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Autores principales: Fabian L. Cardenas-Diaz, Derek C. Liberti, John P. Leach, Apoorva Babu, Jonathan Barasch, Tian Shen, Maria A. Diaz-Miranda, Su Zhou, Yun Ying, Danielle A. Callaway, Michael P. Morley, Edward E. Morrisey
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2023-05-01
Colección:Cell Reports
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Acceso en línea:http://www.sciencedirect.com/science/article/pii/S221112472300462X
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