Mechanisms of loss of functions of human angiogenin variants implicated in amyotrophic lateral sclerosis.
BACKGROUND: Mutations in the coding region of angiogenin (ANG) gene have been found in patients suffering from Amyotrophic Lateral Sclerosis (ALS). Neurodegeneration results from the loss of angiogenic ability of ANG (protein coded by ANG). In this work, we performed extensive molecular dynamics (MD...
保存先:
| 主要な著者: | , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science (PLoS)
2012-01-01
|
| シリーズ: | PLoS ONE |
| オンライン･アクセス: | http://europepmc.org/articles/PMC3288110?pdf=render |
| タグ: |
タグなし, このレコードへの初めてのタグを付けませんか!
|