Mechanisms of loss of functions of human angiogenin variants implicated in amyotrophic lateral sclerosis.
BACKGROUND: Mutations in the coding region of angiogenin (ANG) gene have been found in patients suffering from Amyotrophic Lateral Sclerosis (ALS). Neurodegeneration results from the loss of angiogenic ability of ANG (protein coded by ANG). In this work, we performed extensive molecular dynamics (MD...
Guardat en:
| Autors principals: | , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2012-01-01
|
| Col·lecció: | PLoS ONE |
| Accés en línia: | http://europepmc.org/articles/PMC3288110?pdf=render |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|