Timed secreted proteomes reveal regulation of hepatokines by the liver circadian clock
Abstract Here, we use an ex vivo approach compatible with the circadian timescale to interrogate protein secretion from liver, revealing several findings. Proteomic analyses in male and female mice identify hundreds of proteins that exhibit time-of-day-dependent or clock-dependent secretion involved...
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| Principais autores: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2026-06-01
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| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/s41467-026-73840-4 |
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