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Downregulation of Ripk1 and Nsf mediated by CRISPR-CasRx ameliorates stroke volume and neurological deficits after ischemia stroke in mice

Necroptosis is implicated in the pathogenesis of ischemic stroke. However, the mechanism underlying the sequential recruitment of receptor-interacting protein kinase 1 (RIPK1) and N-ethylmaleimide-sensitive fusion ATPase (NSF) in initiating necroptosis remains poorly understood, and the role of NSF...

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Detaylı Bibliyografya
Asıl Yazarlar: Xincheng Song, Yang Lan, Shuang Lv, Yuye Wang, Leian Chen, Tao Lu, Fei Liu, Dantao Peng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2024-06-01
Seri Bilgileri:Frontiers in Aging Neuroscience
Konular:
Online Erişim:https://www.frontiersin.org/articles/10.3389/fnagi.2024.1401038/full
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