क्यूआर कोड

Oxidative pentose phosphate pathway and glucose anaplerosis support maintenance of mitochondrial NADPH pool under mitochondrial oxidative stress

Abstract Mitochondrial NADPH protects cells against mitochondrial oxidative stress by serving as an electron donor to antioxidant defense systems. However, due to technical challenges, it still remains unknown as to the pool size of mitochondrial NADPH, its dynamics, and NADPH/NADP+ ratio. Here, we...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Sun Jin Moon, Wentao Dong, Gregory N. Stephanopoulos, Hadley D. Sikes
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Wiley 2020-09-01
श्रृंखला:Bioengineering & Translational Medicine
विषय:
hydrogen peroxide
mitochondria
NADPH
NADPH metabolism
NADPH sensor
oxidative stress
ऑनलाइन पहुंच:https://doi.org/10.1002/btm2.10184
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